Mayo Plant
- Capacity: 727 megawatts
- Location: Roxboro, North Carolina
- Commercial Date: 1983

The single-unit, 727-megawatt coal-fired Mayo Plant is located near Roxboro, N.C. It began commercial operation in 1983.

The single-unit, 727-megawatt coal-fired Mayo Plant is located near Roxboro, N.C. It began commercial operation in 1983.